Hey Guitar Player - chambered guitars != solidbody guitars.

Guys like this miss the point.

"So, from a perspective of tone, is there something inherently “wrong” with adding air space to a guitar that would otherwise pass as a traditional solidbody?"

Duh - yes. If you've ever played a classic Gibson Les Paul from before 2005 and compared it to say one of their more recent 'weight-relieved' models, apart from the latter being very expensive, the tone is noticeably thinner.

And more importantly it's not - nor should it be advertised as - a solidbody guitar.

If Gibson or any other guitar manufacturer wants to drill holes into what is advertised or implied as a solidbody guitar, that's their decision - However they should do the honest thing and call that out in their brochures and ads and not call it a solid body guitar, so a customer can know that before they plunk down their hard-earned cash that they'll literally buying quantities of space and air.